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Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms

On activation, the GAL genes in yeast are targeted to the nuclear periphery through interaction with the nuclear pore complex. Here we identify two cis-acting “DNA zip codes” from the GAL1-10 promoter that are necessary and sufficient to induce repositioning to the nuclear periphery. One of these zi...

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Detalles Bibliográficos
Autores principales: Brickner, Donna Garvey, Sood, Varun, Tutucci, Evelina, Coukos, Robert, Viets, Kayla, Singer, Robert H., Brickner, Jason H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042583/
https://www.ncbi.nlm.nih.gov/pubmed/27489341
http://dx.doi.org/10.1091/mbc.E16-03-0174