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Impact of siRNA targeting of β-catenin on differentiation of rat neural stem cells and gene expression of Ngn1 and BMP4 following in vitro hypoxic-ischemic brain damage

The aim of the present study was to investigate the possible damage-repair mechanisms of neural stem cells (NSCs) following hypoxic-ischemic brain damage (HIBD). NSCs obtained from Sprague Dawley rats were treated with tissue homogenate from normal or HIBD tissue, and β-catenin expression was silenc...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoying, Zhu, Cuicui, Luo, Qiong, Dong, Jv, Liu, Lv, Li, Min, Zhu, Hongtao, Ma, Xiangping, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042732/
https://www.ncbi.nlm.nih.gov/pubmed/27573468
http://dx.doi.org/10.3892/mmr.2016.5667