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Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis

Retinoic acid receptor β (RARβ), a known tumor suppressor gene, is frequently silenced in numerous malignant types of tumor. Recent reports have demonstrated that loss of RARβ expression may be responsible, in part, for the drug resistance observed in clinical trials. However, little is known about...

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Detalles Bibliográficos
Autores principales: Ren, Hong-Yue, Chen, Bo, Huang, Gui-Li, Liu, Yu, Shen, Dong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042735/
https://www.ncbi.nlm.nih.gov/pubmed/27599527
http://dx.doi.org/10.3892/mmr.2016.5701