Impact of quercetin-induced changes in drug-metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats

The aim of the present study was to evaluate whether quercetin (Que) modulates the mRNA and protein expression levels of drug-metabolizing enzymes (DMEs) and drug transporters (DTs) in the small intestine and liver, and thus modifies the pharmacokinetic profile of cyclosporine (CsA) in rats. This tw...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yani, Luo, Xiaomei, Yang, Chunxiao, Yang, Tingyu, Zhou, Jiali, Shi, Shaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042751/
https://www.ncbi.nlm.nih.gov/pubmed/27510982
http://dx.doi.org/10.3892/mmr.2016.5616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042751/
https://www.ncbi.nlm.nih.gov/pubmed/27510982
http://dx.doi.org/10.3892/mmr.2016.5616

Ejemplares similares