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The Development of Spasmolytic Polypeptide/TFF2-Expressing Metaplasia (SPEM) During Gastric Repair Is Absent in the Aged Stomach

BACKGROUND & AIMS: During aging, physiological changes in the stomach result in more tenuous gastric tissue that is less capable of repairing injury, leading to increased susceptibility to chronic ulceration. Spasmolytic polypeptide/trefoil factor 2–expressing metaplasia (SPEM) is known to emerg...

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Detalles Bibliográficos
Autores principales: Engevik, Amy C., Feng, Rui, Choi, Eunyoung, White, Shana, Bertaux-Skeirik, Nina, Li, Jing, Mahe, Maxime M., Aihara, Eitaro, Yang, Li, DiPasquale, Betsy, Oh, Sunghee, Engevik, Kristen A., Giraud, Andrew S., Montrose, Marshall H., Medvedovic, Mario, Helmrath, Michael A., Goldenring, James R., Zavros, Yana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042762/
https://www.ncbi.nlm.nih.gov/pubmed/27990460
http://dx.doi.org/10.1016/j.jcmgh.2016.05.004