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Apoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment

Zoledronate is one of the most potent nitrogen-containing bisphosphonates which has been demonstrated to result in osteoblast apoptosis and impact osteogenic differentiation in vitro. This effect of Zoledronate on osteoblasts may partially explain bisphosphonate-associated osteonecrosis of the jaw,...

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Detalles Bibliográficos
Autores principales: Hu, Longwei, Han, Jing, Yang, Xi, Wang, Yang, Pan, Hongya, Xu, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042767/
https://www.ncbi.nlm.nih.gov/pubmed/27573706
http://dx.doi.org/10.3892/mmr.2016.5669