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Punctuated Copy Number Evolution and Clonal Stasis in Triple-Negative Breast Cancer
Aneuploidy is a hallmark of breast cancer; however, our knowledge of how these complex genomic rearrangements evolve during tumorigenesis is limited. In this study we developed a highly multiplexed single-nucleus-sequencing method to investigate copy number evolution in triple-negative breast cancer...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5042845/ https://www.ncbi.nlm.nih.gov/pubmed/27526321 http://dx.doi.org/10.1038/ng.3641 |