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Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action

In this study, the accuracy of the assumption that genotoxic, carcinogenic polycyclic aromatic hydrocarbons (PAHs) act via similar mechanisms of action as benzo(a)pyrene (BaP), the reference PAH used in the human health risk assessment of PAH-containing complex mixtures, was investigated. Adult male...

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Detalles Bibliográficos
Autores principales: Labib, S., Williams, A., Guo, C. H., Leingartner, K., Arlt, V. M., Schmeiser, H. H., Yauk, C. L., White, P. A., Halappanavar, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043007/
https://www.ncbi.nlm.nih.gov/pubmed/26377693
http://dx.doi.org/10.1007/s00204-015-1595-5