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GFAP isoforms control intermediate filament network dynamics, cell morphology, and focal adhesions

Glial fibrillary acidic protein (GFAP) is the characteristic intermediate filament (IF) protein in astrocytes. Expression of its main isoforms, GFAPα and GFAPδ, varies in astrocytes and astrocytoma implying a potential regulatory role in astrocyte physiology and pathology. An IF-network is a dynamic...

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Detalles Bibliográficos
Autores principales: Moeton, Martina, Stassen, Oscar M. J. A., Sluijs, Jacqueline A., van der Meer, Vincent W. N., Kluivers, Liselot J., van Hoorn, Hedde, Schmidt, Thomas, Reits, Eric A. J., van Strien, Miriam E., Hol, Elly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043008/
https://www.ncbi.nlm.nih.gov/pubmed/27141937
http://dx.doi.org/10.1007/s00018-016-2239-5