Efficient GSH delivery using PAMAM-GSH into MPP-induced PC12 cellular model for Parkinson’s disease

Glutathione (GSH) depletion has been an important contributor to the dysfunction of dopamine neurons. Polyamidoamine-GSH (PAMAM-GSH) was synthesized and the delivery effect of GSH into PC12 cells was tested. MTT assessment for cytotoxicity and reactive oxygen species (ROS) as well as nitrite oxide (...

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Detalles Bibliográficos
Autores principales: Sun, Hong-Ji, Wang, Yan, Hao, Tong, Wang, Chang-Yong, Wang, Qi-Yu, Jiang, Xiao-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043156/
https://www.ncbi.nlm.nih.gov/pubmed/27699060
http://dx.doi.org/10.1093/rb/rbw032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043156/
https://www.ncbi.nlm.nih.gov/pubmed/27699060
http://dx.doi.org/10.1093/rb/rbw032

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