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In low protein diets, microRNA-19b regulates urea synthesis by targeting SIRT5

Ammonia detoxification, which takes place via the hepatic urea cycle, is essential for nitrogen homeostasis and physiological well-being. It has been reported that a reduction in dietary protein reduces urea nitrogen. MicroRNAs (miRNAs) are major regulatory non-coding RNAs that have significant effe...

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Detalles Bibliográficos
Autores principales: Sun, Rui-Ping, Xi, Qian-Yun, Sun, Jia-Jie, Cheng, Xiao, Zhu, Yan-Ling, Ye, Ding-Ze, Chen, Ting, Wei, Li-Min, Ye, Rui-Song, Jiang, Qing-Yan, Zhang, Yong-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043173/
https://www.ncbi.nlm.nih.gov/pubmed/27686746
http://dx.doi.org/10.1038/srep33291