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Treatment with Piribedil and Memantine Reduces Noise-Induced Loss of Inner Hair Cell Synaptic Ribbons

Noise overstimulation can induce loss of synaptic ribbons associated with loss of Inner Hair Cell – Auditory Nerve synaptic connections. This study examined if systemic administration of Piribedil, a dopamine agonist that reduces the sound evoked auditory nerve compound action potential and/or Meman...

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Detalles Bibliográficos
Autores principales: Altschuler, Richard A., Wys, Noel, Prieskorn, Diane, Martin, Cathy, DeRemer, Susan, Bledsoe, Sanford, Miller, Josef M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043183/
https://www.ncbi.nlm.nih.gov/pubmed/27686418
http://dx.doi.org/10.1038/srep30821