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Nebivolol Ameliorates Cardiac NLRP3 Inflammasome Activation in a Juvenile-Adolescent Animal Model of Diet-Induced Obesity

NLRP3 is involved in obesity-induced cardiac remodeling and dysfunction. In this study, we evaluated whether the cardiac protective effects of nebivolol relied on attenuating NLRP3 activation in a juvenile-adolescent animal model of diet-induced obesity. Weaning male Sprague-Dawley rats were fed wit...

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Detalles Bibliográficos
Autores principales: Xie, Qihai, Wei, Tong, Huang, Chenglin, Liu, Penghao, Sun, Mengwei, Shen, Weili, Gao, Pingjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043271/
https://www.ncbi.nlm.nih.gov/pubmed/27686325
http://dx.doi.org/10.1038/srep34326