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The impact of P2Y12 promoter DNA methylation on the recurrence of ischemic events in Chinese patients with ischemic cerebrovascular disease

The primary mechanism of clopidogrel resistance is still unclear. We aimed to investigate whether the methylation status of the P2Y12 promoter has effects on platelet function and clinical ischemic events. Patients with ischemic cerebrovascular disease were enrolled into our study. Venous blood samp...

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Detalles Bibliográficos
Autores principales: Li, Xin-Gang, Ma, Ning, Wang, Bo, Li, Xiao-Qing, Mei, Sheng-Hui, Zhao, Kun, Wang, Yong-Jun, Li, Wei, Zhao, Zhi-Gang, Sun, Shu-Sen, Miao, Zhong-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043343/
https://www.ncbi.nlm.nih.gov/pubmed/27686864
http://dx.doi.org/10.1038/srep34570