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Novel proteasome inhibitor ixazomib sensitizes neuroblastoma cells to doxorubicin treatment

Neuroblastoma (NB) is the most common extracranial malignant solid tumor seen in children and continues to lead to the death of many pediatric cancer patients. The poor outcome in high risk NB is largely attributed to the development of chemoresistant tumor cells. Doxorubicin (dox) has been widely e...

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Detalles Bibliográficos
Autores principales: Li, Haoyu, Chen, Zhenghu, Hu, Ting, Wang, Long, Yu, Yang, Zhao, Yanling, Sun, Wenijing, Guan, Shan, Pang, Jonathan C., Woodfield, Sarah E., Liu, Qing, Yang, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043366/
https://www.ncbi.nlm.nih.gov/pubmed/27687684
http://dx.doi.org/10.1038/srep34397