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Adhesive ligand tether length affects the size and length of focal adhesions and influences cell spreading and attachment

Cells are known to respond to physical cues from their microenvironment such as matrix rigidity. Discrete adhesive ligands within flexible strands of fibronectin connect cell surface integrins to the broader extracellular matrix and are thought to mediate mechanosensing through the cytoskeleton-inte...

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Detalles Bibliográficos
Autores principales: Attwood, Simon J., Cortes, Ernesto, Haining, Alexander William M., Robinson, Benjamin, Li, Danyang, Gautrot, Julien, del Río Hernández, Armando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043376/
https://www.ncbi.nlm.nih.gov/pubmed/27686622
http://dx.doi.org/10.1038/srep34334