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Semisynthetic Nanoreactor for Reversible Single-Molecule Covalent Chemistry

[Image: see text] Protein engineering has been used to remodel pores for applications in biotechnology. For example, the heptameric α-hemolysin pore (αHL) has been engineered to form a nanoreactor to study covalent chemistry at the single-molecule level. Previous work has been confined largely to th...

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Detalles Bibliográficos
Autores principales: Lee, Joongoo, Boersma, Arnold J., Boudreau, Marc A., Cheley, Stephen, Daltrop, Oliver, Li, Jianwei, Tamagaki, Hiroko, Bayley, Hagan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043417/
https://www.ncbi.nlm.nih.gov/pubmed/27537396
http://dx.doi.org/10.1021/acsnano.6b04663