Cargando…

A synthetic three-dimensional niche system facilitates generation of functional hematopoietic cells from human-induced pluripotent stem cells

BACKGROUND: The efficient generation of hematopoietic stem cells (HSCs) from human-induced pluripotent stem cells (iPSCs) holds great promise in personalized transplantation therapies. However, the derivation of functional and transplantable HSCs from iPSCs has had very limited success thus far. MET...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yulin, Shan, Wei, Li, Xia, Wang, Binsheng, Liu, Senquan, Wang, Yebo, Long, Yan, Tie, Ruxiu, Wang, Limengmeng, Cai, Shuyang, Zhang, Hao, Lin, Yu, Zhang, Mingming, Zheng, Weiyan, Luo, Yi, Yu, Xiaohong, Yee, Jiing-Kuan, Ji, Junfeng, Huang, He
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043527/
https://www.ncbi.nlm.nih.gov/pubmed/27686241
http://dx.doi.org/10.1186/s13045-016-0326-6