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Different modes of variation for each BG lineage suggest different functions

Mammalian butyrophilins have various important functions, one for lipid binding but others as ligands for co-inhibition of αβ T cells or for stimulation of γδ T cells in the immune system. The chicken BG homologues are dimers, with extracellular immunoglobulin variable (V) domains joined by cysteine...

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Detalles Bibliográficos
Autores principales: Chattaway, John, Ramirez-Valdez, R. Andrei, Chappell, Paul E., Caesar, Joseph J. E., Lea, Susan M., Kaufman, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043582/
https://www.ncbi.nlm.nih.gov/pubmed/27628321
http://dx.doi.org/10.1098/rsob.160188