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Reduced Notch signalling leads to postnatal skeletal muscle hypertrophy in Pofut1(cax/cax) mice

Postnatal skeletal muscle growth results from the activation of satellite cells and/or an increase in protein synthesis. The Notch signalling pathway maintains satellite cells in a quiescent state, and once activated, sustains their proliferation and commitment towards differentiation. In mammals, P...

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Detalles Bibliográficos
Autores principales: Al Jaam, Bilal, Heu, Katy, Pennarubia, Florian, Segelle, Alexandre, Magnol, Laetitia, Germot, Agnès, Legardinier, Sébastien, Blanquet, Véronique, Maftah, Abderrahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043585/
https://www.ncbi.nlm.nih.gov/pubmed/27628322
http://dx.doi.org/10.1098/rsob.160211