A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining

Loss of p53, a transcription factor activated by cellular stress, is a frequent event in cancer. The role of p53 in tumour suppression is largely attributed to cell fate decisions. Here, we provide evidence supporting a novel role for p53 in the regulation of DNA double-strand break (DSB) repair pat...

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Detalles Bibliográficos
Autores principales: Moureau, Sylvie, Luessing, Janna, Harte, Emma Christina, Voisin, Muriel, Lowndes, Noel Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043586/
https://www.ncbi.nlm.nih.gov/pubmed/27655732
http://dx.doi.org/10.1098/rsob.160225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043586/
https://www.ncbi.nlm.nih.gov/pubmed/27655732
http://dx.doi.org/10.1098/rsob.160225

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