Role of autophagy and lysosomal drug sequestration in acquired resistance to doxorubicin in MCF-7 cells

BACKGROUND: The roles and mechanisms involved in starvation-induced autophagy in mammalian cells have been extensively studied. However, less is known about the potential role for autophagy as a survival pathway in acquired drug resistance in cancer cells under nutrient-rich conditions. METHODS: We...

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Detalles Bibliográficos
Autores principales: Guo, Baoqing, Tam, Adam, Santi, Stacey A., Parissenti, Amadeo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043608/
https://www.ncbi.nlm.nih.gov/pubmed/27687594
http://dx.doi.org/10.1186/s12885-016-2790-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043608/
https://www.ncbi.nlm.nih.gov/pubmed/27687594
http://dx.doi.org/10.1186/s12885-016-2790-3

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