Representing and decomposing genomic structural variants as balanced integer flows on sequence graphs

BACKGROUND: The study of genomic variation has provided key insights into the functional role of mutations. Predominantly, studies have focused on single nucleotide variants (SNV), which are relatively easy to detect and can be described with rich mathematical models. However, it has been observed t...

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Detalles Bibliográficos
Autores principales: Zerbino, Daniel R., Ballinger, Tracy, Paten, Benedict, Hickey, Glenn, Haussler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043639/
https://www.ncbi.nlm.nih.gov/pubmed/27687569
http://dx.doi.org/10.1186/s12859-016-1258-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043639/
https://www.ncbi.nlm.nih.gov/pubmed/27687569
http://dx.doi.org/10.1186/s12859-016-1258-4

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