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Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation

α-Synuclein is a soluble, cellular protein that in a number of neurodegenerative diseases, including Parkinson's disease and multiple system atrophy, forms pathological deposits of protein aggregates. Because misfolded α-synuclein has some characteristics that resemble those of prions, we inves...

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Detalles Bibliográficos
Autores principales: Breid, Sara, Bernis, Maria E., Babila, Julius T., Garza, Maria C., Wille, Holger, Tamgüney, Gültekin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044858/
https://www.ncbi.nlm.nih.gov/pubmed/27489279
http://dx.doi.org/10.1128/JVI.01399-16