Cargando…

Neuroinvasion of α-Synuclein Prionoids after Intraperitoneal and Intraglossal Inoculation

α-Synuclein is a soluble, cellular protein that in a number of neurodegenerative diseases, including Parkinson's disease and multiple system atrophy, forms pathological deposits of protein aggregates. Because misfolded α-synuclein has some characteristics that resemble those of prions, we inves...

Descripción completa

Detalles Bibliográficos
Autores principales:	Breid, Sara, Bernis, Maria E., Babila, Julius T., Garza, Maria C., Wille, Holger, Tamgüney, Gültekin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Prions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044858/ https://www.ncbi.nlm.nih.gov/pubmed/27489279 http://dx.doi.org/10.1128/JVI.01399-16

Ejemplares similares

Oral Prion Neuroinvasion Occurs Independently of PrP(C) Expression in the Gut Epithelium
por: Marshall, Alison, et al.
Publicado: (2018)

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains
por: Duque Velásquez, Camilo, et al.
Publicado: (2015)

Prion-like propagation of human brain-derived alpha-synuclein in transgenic mice expressing human wild-type alpha-synuclein
por: Bernis, Maria E., et al.
Publicado: (2015)

The Glycosylation Status of PrP(C) Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species
por: Wiseman, Frances K., et al.
Publicado: (2015)

Defining the Microglia Response during the Time Course of Chronic Neurodegeneration
por: Vincenti, James E., et al.
Publicado: (2016)

The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis
por: Donaldson, David S., et al.
Publicado: (2015)

Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells
por: Bradford, Barry M., et al.
Publicado: (2017)

Therapeutic Trial of anle138b in Mouse Models of Genetic Prion Disease
por: Vallabh, Sonia M., et al.
Publicado: (2023)

Oral and intravenous transmission of α-synuclein fibrils to mice
por: Lohmann, Stephanie, et al.
Publicado: (2019)

Introduction: Invited Speakers
Publicado: (2013)

α‐Synuclein: The Long Distance Runner
por: George, Sonia, et al.
Publicado: (2013)

Ischemic stroke causes Parkinson’s disease-like pathology and symptoms in transgenic mice overexpressing alpha-synuclein
por: Lohmann, Stephanie, et al.
Publicado: (2022)

Prionoids in amyotrophic lateral sclerosis
por: Gosset, Philippe, et al.
Publicado: (2022)

Prionoid Proteins in the Pathogenesis of Neurodegenerative Diseases
por: Wells, Cameron, et al.
Publicado: (2019)

Submucosal Intraglossal Fish Bone Extraction: A Case for the Multidisciplinary Team
por: Olley, Benjamin M, et al.
Publicado: (2021)

Prions, prionoids and pathogenic proteins in Alzheimer disease
por: Ashe, Karen H., et al.
Publicado: (2013)

Prions, prion-like prionoids, and neurodegenerative disorders
por: Verma, Ashok
Publicado: (2016)

ASC has extracellular and prionoid activities that propagate inflammation
por: Franklin, Bernardo S., et al.
Publicado: (2014)

A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization
por: Wüsten, Katharina Annick, et al.
Publicado: (2018)

Outlining Core Pathways of Amyloid Toxicity in Bacteria with the RepA-WH1 Prionoid
por: Molina-García, Laura, et al.
Publicado: (2017)

Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy
por: Ferreira, Nelson, et al.
Publicado: (2021)

Correction to: Prodromal neuroinvasion of pathological α-synuclein in brainstem reticular nuclei and white matter lesions in a model of α-synucleinopathy
por: Ferreira, Nelson, et al.
Publicado: (2022)

Pre-amyloid oligomers of the proteotoxic RepA-WH1 prionoid assemble at the bacterial nucleoid
por: Moreno-del Álamo, María, et al.
Publicado: (2015)

RepA-WH1 prionoid: Clues from bacteria on factors governing phase transitions in amyloidogenesis
por: Giraldo, Rafael, et al.
Publicado: (2016)

Low morbidity high anterior neck approach for removal of a deep intraglossal foreign body: A case report
por: Sideris, Anders W., et al.
Publicado: (2021)

Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers
por: Boi, Laura, et al.
Publicado: (2020)

Intraperitoneal Inoculation: An Atypical Route of Trichinella spiralis Infection
por: JIANG, Peng, et al.
Publicado: (2017)

Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
por: Luk, Kelvin C., et al.
Publicado: (2012)

Biological Responses in the Blood and Organs of Rats to Intraperitoneal Inoculation of Graphene and Graphene Oxide
por: Aguado-Henche, Soledad, et al.
Publicado: (2022)

Antiviral Cytokine Response in Neuroinvasive and Non-Neuroinvasive West Nile Virus Infection
por: Zidovec-Lepej, Snjezana, et al.
Publicado: (2021)

Neuroinvasion and Encephalitis Following Intranasal Inoculation of SARS-CoV-2 in K18-hACE2 Mice
por: Kumari, Pratima, et al.
Publicado: (2021)

Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting
por: Blömeke, Lara, et al.
Publicado: (2022)

Ageing promotes pathological alpha-synuclein propagation and autonomic dysfunction in wild-type rats
por: Van Den Berge, Nathalie, et al.
Publicado: (2021)

GI infections are associated with an increased risk of Parkinson’s disease
por: Nerius, Michael, et al.
Publicado: (2020)

Recurring Gastrointestinal Infections Increase the Risk of Dementia
por: Fink, Anne, et al.
Publicado: (2021)

INFLUENCE OF HOST FACTORS ON NEUROINVASIVENESS OF VESICULAR STOMATITIS VIRUS : IV. VARIATIONS IN NEUROINVASIVENESS IN DIFIERENT SPECIES
por: Sabin, Albert B., et al.
Publicado: (1938)

INFLUENCE OF HOST FACTORS ON NEUROINVASIVENESS OF VESICULAR STOMATITIS VIRUS : IV. VARIATIONS IN NEUROINVASIVENESS IN DIFIERENT SPECIES
por: Sabin, Albert B., et al.
Publicado: (1938)

Progressive cognitive impairment after recovery from neuroinvasive and non-neuroinvasive Listeria monocytogenes infection
por: Cassidy, Benjamin R., et al.
Publicado: (2023)

Evidence for bidirectional and trans-synaptic parasympathetic and sympathetic propagation of alpha-synuclein in rats
por: Van Den Berge, Nathalie, et al.
Publicado: (2019)

Übertragungswege neuropathogener Erreger – mögliche Mechanismen der Neuroinvasion
por: Craemer, Eva Maria
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_06bjsvtaohpi6rfvie4t5d16c2