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Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-1) and soluble urokinase-type plasminogen activator receptor (suPAR) participate in inflammation and tissue remolding in various diseases, but their roles in chronic obstructive pulmonary disease (COPD) are not yet clear. This study aimed to investi...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Yang, Ting, Li, Diandian, Wu, Yanqiu, Zhang, Xue, Pang, Caishuang, Zhang, Junlong, Ying, Binwu, Wang, Tao, Wen, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5044991/
https://www.ncbi.nlm.nih.gov/pubmed/27713627
http://dx.doi.org/10.2147/COPD.S107409