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Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β

Hypoxia-inducible factors (HIFs), consisting of α- and β-subunits, are critical regulators of the transcriptional response to hypoxia under both physiological and pathological conditions. To a large extent, the protein stability and the recruitment of coactivators to the C-terminal transactivation d...

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Detalles Bibliográficos
Autores principales: Mennerich, Daniela, Dimova, Elitsa Y, Kietzmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045055/
https://www.ncbi.nlm.nih.gov/pubmed/27774465
http://dx.doi.org/10.2147/HP.S60703