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Direct phosphorylation events involved in HIF-α regulation: the role of GSK-3β
Hypoxia-inducible factors (HIFs), consisting of α- and β-subunits, are critical regulators of the transcriptional response to hypoxia under both physiological and pathological conditions. To a large extent, the protein stability and the recruitment of coactivators to the C-terminal transactivation d...
Autores principales: | Mennerich, Daniela, Dimova, Elitsa Y, Kietzmann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045055/ https://www.ncbi.nlm.nih.gov/pubmed/27774465 http://dx.doi.org/10.2147/HP.S60703 |
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