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HIF-mediated innate immune responses: cell signaling and therapeutic implications

Leukocytes recruited to infected, damaged, or inflamed tissues during an immune response must adapt to oxygen levels much lower than those in the circulation. Hypoxia inducible factors (HIFs) are key mediators of cellular responses to hypoxia and, as in other cell types, HIFs are critical for the up...

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Detalles Bibliográficos
Autores principales: Harris, Alison J, Thompson, AA Roger, Whyte, Moira KB, Walmsley, Sarah R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045056/
https://www.ncbi.nlm.nih.gov/pubmed/27774466
http://dx.doi.org/10.2147/HP.S50269