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Effects of copper sulfate-oxidized or myeloperoxidase-modified LDL on lipid loading and programmed cell death in macrophages under hypoxia

Atheromatous plaques contain heavily lipid-loaded macrophages that die, hence generating the necrotic core of these plaques. Since plaque instability and rupture is often correlated with a large necrotic core, it is important to understand the mechanisms underlying foam cell death. Furthermore, macr...

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Detalles Bibliográficos
Autores principales: Vlaminck, Benoit, Calay, Damien, Genin, Marie, Sauvage, Aude, Ninane, Noelle, Zouaoui Boudjeltia, Karim, Raes, Martine, Michiels, Carine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045064/
https://www.ncbi.nlm.nih.gov/pubmed/27774474
http://dx.doi.org/10.2147/HP.S65242