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Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
By the early 1900s, the close matching of oxygen supply with demand was recognized to be a fundamental requirement for physiological function, and multiple adaptive responses to environment hypoxia had been described. Nevertheless, the widespread operation of mechanisms that directly sense and respo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045067/ https://www.ncbi.nlm.nih.gov/pubmed/27774477 http://dx.doi.org/10.2147/HP.S47598 |