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PU-H71, a novel Hsp90 inhibitor, as a potential cancer-specific sensitizer to carbon-ion beam therapy

PU-H71, a heat shock protein 90 (Hsp90) inhibitor, has yielded therapeutic efficacy in many preclinical models and is currently in clinical trials. Carbon-ion radiotherapy (CIRT) has provided successful tumor control; however, there is still room for improvement, particularly in terms of tumor-speci...

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Detalles Bibliográficos
Autores principales: Li, Huizi Keiko, Matsumoto, Yoshitaka, Furusawa, Yoshiya, Kamada, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045081/
https://www.ncbi.nlm.nih.gov/pubmed/27242340
http://dx.doi.org/10.1093/jrr/rrw054