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The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy

Hypoxia is a non-physiological level of oxygen tension, a phenomenon common in a majority of malignant tumors. Tumor-hypoxia leads to advanced but dysfunctional vascularization and acquisition of epithelial-to-mesenchymal transition phenotype resulting in cell mobility and metastasis. Hypoxia alters...

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Detalles Bibliográficos
Autores principales: Muz, Barbara, de la Puente, Pilar, Azab, Feda, Azab, Abdel Kareem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045092/
https://www.ncbi.nlm.nih.gov/pubmed/27774485
http://dx.doi.org/10.2147/HP.S93413