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Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody

Staphylococcus aureus is a major human pathogen associated with high mortality. The emergence of antibiotic resistance and the inability of antibiotics to counteract bacterial cytotoxins involved in the pathogenesis of S. aureus call for novel therapeutic approaches, such as passive immunization wit...

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Detalles Bibliográficos
Autores principales: Rouha, Harald, Badarau, Adriana, Visram, Zehra C, Battles, Michael B, Prinz, Bianka, Magyarics, Zoltán, Nagy, Gábor, Mirkina, Irina, Stulik, Lukas, Zerbs, Manuel, Jägerhofer, Michaela, Maierhofer, Barbara, Teubenbacher, Astrid, Dolezilkova, Ivana, Gross, Karin, Banerjee, Srijib, Zauner, Gerhild, Malafa, Stefan, Zmajkovic, Jakub, Maier, Sabine, Mabry, Robert, Krauland, Eric, Wittrup, K Dane, Gerngross, Tillman U, Nagy, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045134/
https://www.ncbi.nlm.nih.gov/pubmed/25523282
http://dx.doi.org/10.4161/19420862.2014.985132