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The Impact of the Gut Microbiota on Drug Metabolism and Clinical Outcome

The significance of the gut microbiota as a determinant of drug pharmacokinetics and accordingly therapeutic response is of increasing importance with the advent of modern medicines characterised by low solubility and/or permeability, or modified-release. These physicochemical properties and release...

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Detalles Bibliográficos
Autores principales: Enright, Elaine F., Gahan, Cormac G.M., Joyce, Susan A., Griffin, Brendan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045146/
https://www.ncbi.nlm.nih.gov/pubmed/27698621