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Prion Aggregates Are Recruited to the Insoluble Protein Deposit (IPOD) via Myosin 2-Based Vesicular Transport

Aggregation of amyloidogenic proteins is associated with several neurodegenerative diseases. Sequestration of misfolded and aggregated proteins into specialized deposition sites may reduce their potentially detrimental properties. Yeast exhibits a distinct deposition site for amyloid aggregates term...

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Detalles Bibliográficos
Autores principales: Kumar, Rajesh, Nawroth, Peter P., Tyedmers, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045159/
https://www.ncbi.nlm.nih.gov/pubmed/27689885
http://dx.doi.org/10.1371/journal.pgen.1006324