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Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells

Dexrazoxane has been approved to treat anthracycline-induced cardiomyopathy and extravasation. However, the effect of dexrazoxane on epirubicin-induced genetic alterations in germ cells has not yet been reported. Thus, the aim of this study was to determine whether dexrazoxane modulates epirubicin-i...

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Detalles Bibliográficos
Autores principales: Attia, Sabry M., Ahmad, Sheikh F., Ansaria, Mushtaq A., Nadeem, Ahmed, Al-Shabanah, Othman A., Al-Harbi, Mohammed M., Bakheet, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045162/
https://www.ncbi.nlm.nih.gov/pubmed/27690233
http://dx.doi.org/10.1371/journal.pone.0163703