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Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans

The translation initiation factor eIF3 is a multi-subunit protein complex that coordinates the assembly of the 43S pre-initiation complex in eukaryotes. Prior studies have demonstrated that not all subunits of eIF3 are essential for the initiation of translation, suggesting that some subunits may se...

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Detalles Bibliográficos
Autores principales: Cattie, Douglas J., Richardson, Claire E., Reddy, Kirthi C., Ness-Cohn, Elan M., Droste, Rita, Thompson, Mary K., Gilbert, Wendy V., Kim, Dennis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045169/
https://www.ncbi.nlm.nih.gov/pubmed/27690135
http://dx.doi.org/10.1371/journal.pgen.1006326