Anchoring of Heterochromatin to the Nuclear Lamina Reinforces Dosage Compensation-Mediated Gene Repression

Higher order chromosome structure and nuclear architecture can have profound effects on gene regulation. We analyzed how compartmentalizing the genome by tethering heterochromatic regions to the nuclear lamina affects dosage compensation in the nematode C. elegans. In this organism, the dosage compe...

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Detalles Bibliográficos
Autores principales: Snyder, Martha J., Lau, Alyssa C., Brouhard, Elizabeth A., Davis, Michael B., Jiang, Jianhao, Sifuentes, Margarita H., Csankovszki, Györgyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045178/
https://www.ncbi.nlm.nih.gov/pubmed/27690361
http://dx.doi.org/10.1371/journal.pgen.1006341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045178/
https://www.ncbi.nlm.nih.gov/pubmed/27690361
http://dx.doi.org/10.1371/journal.pgen.1006341

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