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ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics

Centrosomes are critical sites for orchestrating microtubule dynamics, and exhibit dynamic changes in size during the cell cycle. As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure proper chromosome segregation. We report a new role...

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Detalles Bibliográficos
Autores principales: Stubenvoll, Michael D., Medley, Jeffrey C., Irwin, Miranda, Song, Mi Hye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045193/
https://www.ncbi.nlm.nih.gov/pubmed/27689799
http://dx.doi.org/10.1371/journal.pgen.1006370