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ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics
Centrosomes are critical sites for orchestrating microtubule dynamics, and exhibit dynamic changes in size during the cell cycle. As cells progress to mitosis, centrosomes recruit more microtubules (MT) to form mitotic bipolar spindles that ensure proper chromosome segregation. We report a new role...
Autores principales: | Stubenvoll, Michael D., Medley, Jeffrey C., Irwin, Miranda, Song, Mi Hye |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045193/ https://www.ncbi.nlm.nih.gov/pubmed/27689799 http://dx.doi.org/10.1371/journal.pgen.1006370 |
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