The Organophosphate Paraoxon and Its Antidote Obidoxime Inhibit Thrombin Activity and Affect Coagulation In Vitro

Organophosphates (OPs) are potentially able to affect serine proteases by reacting with their active site. The potential effects of OPs on coagulation factors such as thrombin and on coagulation tests have been only partially characterized and potential interactions with OPs antidotes such as oximes...

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Detalles Bibliográficos
Autores principales: Golderman, Valery, Shavit-Stein, Efrat, Tamarin, Ilia, Rosman, Yossi, Shrot, Shai, Rosenberg, Nurit, Maggio, Nicola, Chapman, Joab, Eisenkraft, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045196/
https://www.ncbi.nlm.nih.gov/pubmed/27689805
http://dx.doi.org/10.1371/journal.pone.0163787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045196/
https://www.ncbi.nlm.nih.gov/pubmed/27689805
http://dx.doi.org/10.1371/journal.pone.0163787

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