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Preparation and evaluation of a self-nanoemulsifying drug delivery system loaded with Akebia saponin D–phospholipid complex

BACKGROUND: Akebia saponin D (ASD) exerts various pharmacological activities but with poor oral bioavailability. In this study, a self-nanoemulsifying drug delivery system (SNEDDS) based on the drug–phospholipid complex technique was developed to improve the oral absorption of ASD. METHODS: ASD–phos...

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Detalles Bibliográficos
Autores principales: Shen, Jinyang, Bi, Jianping, Tian, Hongli, Jin, Ye, Wang, Yuan, Yang, Xiaolin, Yang, Zhonglin, Kou, Junping, Li, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045231/
https://www.ncbi.nlm.nih.gov/pubmed/27713630
http://dx.doi.org/10.2147/IJN.S108765