Adequate sample size for developing prediction models is not simply related to events per variable

OBJECTIVES: The choice of an adequate sample size for a Cox regression analysis is generally based on the rule of thumb derived from simulation studies of a minimum of 10 events per variable (EPV). One simulation study suggested scenarios in which the 10 EPV rule can be relaxed. The effect of a rang...

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Detalles Bibliográficos
Autores principales: Ogundimu, Emmanuel O., Altman, Douglas G., Collins, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045274/
https://www.ncbi.nlm.nih.gov/pubmed/26964707
http://dx.doi.org/10.1016/j.jclinepi.2016.02.031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045274/
https://www.ncbi.nlm.nih.gov/pubmed/26964707
http://dx.doi.org/10.1016/j.jclinepi.2016.02.031

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