Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A

The kinesin-8 motor, KIF19A, accumulates at cilia tips and controls cilium length. Defective KIF19A leads to hydrocephalus and female infertility because of abnormally elongated cilia. Uniquely among kinesins, KIF19A possesses the dual functions of motility along ciliary microtubules and depolymeriz...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Doudou, Nitta, Ryo, Morikawa, Manatsu, Yajima, Hiroaki, Inoue, Shigeyuki, Shigematsu, Hideki, Kikkawa, Masahide, Hirokawa, Nobutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045296/
https://www.ncbi.nlm.nih.gov/pubmed/27690357
http://dx.doi.org/10.7554/eLife.18101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045296/
https://www.ncbi.nlm.nih.gov/pubmed/27690357
http://dx.doi.org/10.7554/eLife.18101

Ejemplares similares