Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by an accumulation of clonal plasma cells in the bone marrow leading to bone destruction and bone marrow failure. Several molecular mechanisms underlie chemoresistance among which heme oxygenase-1 (HO-1) could play a major role. The a...

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Detalles Bibliográficos
Autores principales: Tibullo, Daniele, Barbagallo, Ignazio, Giallongo, Cesarina, Vanella, Luca, Conticello, Concetta, Romano, Alessandra, Saccone, Salvatore, Godos, Justyna, Di Raimondo, Francesco, Li Volti, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045362/
https://www.ncbi.nlm.nih.gov/pubmed/26930712
http://dx.doi.org/10.18632/oncotarget.7563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045362/
https://www.ncbi.nlm.nih.gov/pubmed/26930712
http://dx.doi.org/10.18632/oncotarget.7563

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