Functional genomics screen identifies YAP1 as a key determinant to enhance treatment sensitivity in lung cancer cells

Survival for lung cancer patients remains dismal and is largely attributed to treatment resistance. To identify novel target genes the modulation of which could modify platinum resistance, we performed a high-throughput RNAi screen and identified Yes-associated protein (YAP1), a transcription coacti...

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Detalles Bibliográficos
Autores principales: Cheng, Haiying, Zhang, Zhenfeng, Rodriguez-Barrueco, Ruth, Borczuk, Alain, Liu, Huijie, Yu, Jiyang, Silva, Jose M., Cheng, Simon K., Perez-Soler, Roman, Halmos, Balazs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045371/
https://www.ncbi.nlm.nih.gov/pubmed/26716514
http://dx.doi.org/10.18632/oncotarget.6721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045371/
https://www.ncbi.nlm.nih.gov/pubmed/26716514
http://dx.doi.org/10.18632/oncotarget.6721

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