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Autophagy-related cell death by pan-histone deacetylase inhibition in liver cancer

Autophagy is a homeostatic, catabolic degradation process and cell fate essential regulatory mechanism. Protracted autophagy triggers cell death; its aberrant function is responsible for several malignancies. Panobinostat, a potent pan-deacetylase inhibitor, causes endoplasmic reticulum stress-induc...

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Detalles Bibliográficos
Autores principales: Di Fazio, Pietro, Waldegger, Petra, Jabari, Samir, Lingelbach, Susanne, Montalbano, Roberta, Ocker, Matthias, Slater, Emily P., Bartsch, Detlef K., Illig, Romana, Neureiter, Daniel, Wissniowski, Thaddeus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045373/
https://www.ncbi.nlm.nih.gov/pubmed/27058414
http://dx.doi.org/10.18632/oncotarget.8585