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Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis

Hypoxia, a common condition of the tumor microenvironment, is associated with poor patient prognosis, tumor cell migration, invasion and metastasis. Recent evidence suggests that hypoxia alters endosome dynamics in tumor cells, leading to augmented cell proliferation and migration and this is partic...

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Detalles Bibliográficos
Autores principales: Silva, Patricio, Mendoza, Pablo, Rivas, Solange, Díaz, Jorge, Moraga, Carolina, Quest, Andrew F.G., Torres, Vicente A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045416/
https://www.ncbi.nlm.nih.gov/pubmed/27121131
http://dx.doi.org/10.18632/oncotarget.8794