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Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis
Hypoxia, a common condition of the tumor microenvironment, is associated with poor patient prognosis, tumor cell migration, invasion and metastasis. Recent evidence suggests that hypoxia alters endosome dynamics in tumor cells, leading to augmented cell proliferation and migration and this is partic...
Autores principales: | Silva, Patricio, Mendoza, Pablo, Rivas, Solange, Díaz, Jorge, Moraga, Carolina, Quest, Andrew F.G., Torres, Vicente A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045416/ https://www.ncbi.nlm.nih.gov/pubmed/27121131 http://dx.doi.org/10.18632/oncotarget.8794 |
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